Patrik Edén

Publications at division for computational biology and biological physics.

• J. Kalderstam, P. Edén, P-O. Bendahl, C. Strand, M. Fernö and M. Ohlsson
  Training artificial neural networks directly on the concordance index for censored data using genetic algorithms
  Artificial Intelligence in Medicine, http://dx.doi.org/10.1016/j.artmed.2013.03.001, (2013)
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• K. Rydström, P. Joost, M. Ehinger, P. Edén, M. Jerkeman, E. Cavallin-Ståhl and J. Linderoth
  Gene expression profiling indicates that immunohistochemical expression of CD40 is a marker of an inflammatory reaction in the tumor stroma of diffuse large B-cell lymphoma
  Leuk Lymphoma 53, 1764-1768 (2012)
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• A. Andersson, P. Edén, T. Olofsson and T. Fioretos
  Gene expression signatures in childhood acute leukemias are largely unique and distinct from those of normal tissues and other malignancies
  BMC Med Genomics 3, 6 (2010)
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• U. Andréasson, P. Edén, C. Peterson, C-M. Högerkorp, M. Jerkeman, N. Andersen, M. Berglund, C. Sundström, R. Rosenquist, C.A.K. Borrebaeck and S. Ek
  Identification of uniquely expressed transcription factors in highly purified B-cell lymphoma samples
  American Journal of Hematology 85:418-425 (2010)
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• M. Järås, P. Johnels, H. Ågerstam, C. Lassen, M. Rissler, P. Edén, J. Cammenga, T. Olofsson, O.W. Bjerrum, J. Richter, X. Fan and T. Fioretos
  Expression of P190 and P210 BCR/ABL1 in normal human CD34(+) cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage
  Experimental Hematology 37:367-375 (2009)
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• C. Ritz and P. Edén
  Accounting for one-channel depletion improves missing value imputation in 2-dye microarray data
  BMC Genomics 19:25 (2008)
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• J. Linderoth, P. Edén, M. Ehinger, J. Valcich, M. Jerkeman, P.-O. Bendahl, M. Berglund, G. Enblad, M. Erlanson, G. Roos and E. Cavallin-Ståhl
  Genes associatied with the tumor microenvironment are differentially expressed in cured versus primary chemotherapy-refractory diffuse large B-cell lymphoma
  British Journal of Haematology 141:423-432 (2008)
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• L. Nilsson, P. Edén, E. Olsson, R. Månsson, I. Åstrand-Grundström, B. Strömbeck, K. Theilgaard-Moench, K. Anderson, R. Hast, E. Hellström-Lindberg, J. Samuelsson, G. Bergh, C. Nerlov, B. Johansson, M. Sigvardsson, Å Borg and S.E. Jacobsen
  The molecular signature of MDS stem cells supports a stem cell origin of 5q- myelodysplastic syndromes
  Blood 110, 3005-3014 (2007)
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• P. Francis, H.M. Namløs, C. Müller, P. Edén, J. Fernebro, J.-M. Berner, B. Bjerkehagen, M. Åkerman, P.-O. Bendahl, A. Isinger, A. Rydholm, O.Myklebost and M. Nilbert
  Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: hypoxia-induced transcription profile signifies metastatic potential
  BMC Genomics 8, 73 (2007)
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• P.R. Painter, P. Edén and H.-U. Bengtsson
  Pulsatile blood flow, shear force, energy dissipation and Murray's Law
  Theoretical Biology and Medical Modelling 3, 31 (2006)
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• A. Andersson, C. Ritz, D. Lindgren, P. Edén, C. Lassen, J. Heldrup, T. Olofsson, J. Råde, M. Fontes, A. Porwit-McDonald, M. Behrendtz, M. Höglund, B. Johansson and T. Fioretos
  Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status
  Leukemia 21, 1198-1203 (2007)
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• A. Andersson, T. Olofsson, D. Lindgren, B. Nilsson, C. Ritz, P. Edén, C. Lassen, J. Råde, M. Fontes, H. Mörse, J. Heldrup, M. Behrendtz, F. Mitelman, M. Höglund, B. Johansson and T. Fioretos
  Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations
  PNAS 102, 19069-19074 (2005)
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• S.K. Gruvberger-Saal, P-O. Bendahl, L.H. Saal, M. Laakso, P. Edén, C. Peterson, P. Malmström, J. Isola, Å. Borg and M. Fernö
  Estrogen Receptor (ER) beta Expression is Associated with Tamoxifen Response in ER alpha-negative breast carcinoma
  Clinical Cancer Research 13,1987-1994 (2007)
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• E. Niméus-Malmström, C. Ritz, P. Edén, A. Johnsson, C. Strand, G. Östberg, M. Fernö and C. Peterson
  Gene expression profilers and conventional clinical markers to predict distant recurrences for premenopausal breast cancer patients after adjuvant chemotherapy (CMF)
  European Journal of Cancer 42, 2729-2737 (2006)
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• J. Fernebro, P. Francis, P. Edén, Å. Borg, I. Panagopoulos, F. Mertens, J. Vallon-Christersson, M. Åkerman, N. Mandahl and M. Nilbert
  Gene expression profiles relate to SS18/SSX fusion type and development of metastasis in synovial sarcoma
  Int J Cancer 118, 1165-1172 (2006)
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• P. Francis, J. Fernebro, P. Edén, A. Laurell, A. Rydholm, H.A. Domanski, T. Breslin, C. Hegardt, Å. Borg and M. Nilbert
  Intratumor versus intertumor heterogeneity in gene expression profiles from soft tissue sarcoma
  Genes Chromosomes Cancer 3, 302-308 (2005)
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• A. Andersson, P. Edén, D. Lindgren, J. Nilsson, C. Lassen, J. Heldrup, M. Fontes, Å. Borg, F. Mittelman, B. Johansson, M. Höglund and T. Fioretos
  Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations
  Leukemia 19, 1042-1050 (2005)
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• T. Breslin, P. Edén and M. Krogh
  Comparing functional annotation analyses with catmap
  BMC Bioinformatics 5, 193 (2004)
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• P. Edén, C. Ritz, C. Rose, M. Fernö and C. Peterson
  ''Good old'' clinical markers have similar power in breast cancer prognosis as microarray gene expression profilers
  European Journal of Cancer 40, 1837-1841 (2004)
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• S.K. Gruvberger-Saal, P. Edén, M. Ringnér, B. Baldetorp, G. Chebil, Å. Borg, M. Fernö, C. Peterson and P.S. Meltzer
  Predicting continuous values of prognostic markers in breast cancer from microarray gene expression profiles
  molecular cancer therapeutics 3, 161-168 (2004)
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• H.-U. Bengtsson and P. Edén
  A simple model for the arterial system
  Journal of Theoretical Biology 221, 437-443 (2003)
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• S.K. Gruvberger, M. Ringnér, P. Edén, Å. Borg, M. Fernö, C. Peterson and P.S. Meltzer
  Expression profiling to predict outcome in breast cancer: the influence of sample selection
  Breast Cancer Research 5, 23-26 (2003)
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• M. Ringnér, P. Edén and P. Johansson
  Classification of expression patterns using artificial neural networks
  In A Practical Approach to Microarray Data Analysis, eds. D.P. Berrar, W. Dubitzky and M. Granzow, 201-215 (Kluwer Academic Publishers, 2002)
  [Abstract] [PDF]